Assessment of Cerebral Hemodynamics in Traumatic Brain Injury
نویسندگان
چکیده
We employ complex continuous wavelet transforms to develop a consistent mathematical framework capable of quantifying both cerebrospinal compensatory reserve and cerebrovascular pressure–reactivity. The wavelet gain ( ) ICP ABP f η , defined as the frequency dependent ratio of time averaged wavelet coefficients of intracranial pressure (ICP) and arterial blood pressure (ABP) fluctuations, characterizes the dampening of spontaneous ABP oscillations. This gain is introduced as a novel measure of cerebrospinal compensatory reserve. For a group of 12 patients who died as a result of cerebral lesions (Glasgow Outcome Scale GOS =1) the average gain calculated at f=0.05 Hz significantly exceeds that of 17 patients with GOS=2: with 0.45 ICP
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